New Orleans, 1853. A young Zapotec exile from Mexico named Benito Juárez disembarks at a fetid port city at the edge of a swamp. Years later, he will become the first indigenous head of state in the postcolonial Americas, but now he is as anonymous and invisible as any other migrant to the roiling and alluring city.

Accompanied by a small group of fellow exiles who plot their return and hoped-for victory over the Mexican dictatorship, Juárez immerses himself in the city, which absorbs him like a sponge. He and his compatriots work odd jobs, fall victim to the cons and confusions of a strange young nation, succumb to the hallucinations of yellow fever, and fall in love with the music and food all around them. But unavoidable, too, is the stark trade in human beings.